Scaring Yourself With Sounds

I have a dentist appointment this morning, so why am I thinking about Marathon Man! You know the scene with Dustin Hoffman, the 64th scariest scene of all time. It's the type of scene that would make everyone cringe, except, of course, Jack Nicholson in the original The Little Shop of Horrors. (Not to be confused with Susan Goodwill's Little Shop of Murders, a most excellent cozy mystery novel.) There's something very unnerving about that high-pitched, whirling sound with which most everyone can associate.

What other universally disturbing sounds are there that make your readers cringe?